Humans beings are unavoidably exposed to ambient electromagnetic fields (EMF) generated from various electrical devices and from power transmission lines. All of the electronic equipment’s that we use in our daily life without thinking how much we use or how often we use creates EMF. With the ever-increasing use of the electric technology, electromagnetic fields especially the extremely low frequency electromagnetic fields (ELF-EMF) have become a part of the modern life. These fields are produced by all electric devices, including high energy sources like power lines and microwaves, but also found in low energy devices such as cell phones. In exposed rat group to 50 Hz horizontal electric field for 8 hours/ day for 8 weeks, many histological alterations such as focal tubular atrophy, necrosis and degeneration of the seminiferous epithelium were observed in the testes. Moreover, Zare et al. clarified that the exposed group of guinea pigs to 50 Hz electric field for 2 hours daily for 5 days cause cytoplasmic vacuolations of the hepatocytes. Furthermore, swelling in the epithelial cells of renal tubules and subsequently cell necrosis were observed with glomerular dilatation. And also, atrophy of the seminiferous tubules was detected. It was reported that extremely low frequency EMF induced tissue damage in different organs of the experimental animals. Also, exposure to MF adversely affects spermatogenesis, Sertoli and Leydig cells of experimental animals. Recently, the histological and physiological studies have increased in the evaluation of the effects of electromagnetic fields on human health.