Malaria is a life-threatening mosquito-borne infectious disease causing a major public health problem in the world mainly on children under five years of age.The disease is widespread in the tropical and subtropical regions that exist in a broadband around the equator. This includes much of Sub-Saharan Africa, Asia, and Latin America  Nearly half of the world's population is at risk of malaria with around 212 million new cases and 429,000 deaths annually approximately 90% of both cases and deaths occurred in Africa. In Ethiopia malaria is ranked as the leading communicable disease resulting in 29% deaths in most part of the country.Malaria has a major negative effect on economic development. In Africa, it is estimated to result in losses of US$12 billion a year due to increased healthcare costs, lost ability to work, and negative effects on tourism.